Spent Media Analysis Suggests Cultivated Meat Media Will Require Species and Cell Type Optimization

Overview

Who: Edward N. O’Neill, Joshua C. Ansel, Grace A. Kwong, Michael E. Plastino, Jenny Nelson, Keith Baar, David E. Block

Published: September 29, 2022

Where: npj Science of Food

Key Takeaway: Growth media should be customized to the cells it will be used to culture to reduce cost and waste in cultivated meat production.

Research Topics: media

Summary

Edward O’Neill et al. clarify assumptions about development and optimization of cultivated meat growth media. They track concentrations of numerous components of growth media throughout the culture of chicken muscle precursor cells, chicken muscle fibroblasts, and mouse myoblasts. O’Neill et al. determine component consumption can vary greatly between even similar cell types (e.g., chicken muscle precursor cells vs. fibroblasts), and that some components are in great excess in commercial growth media. They argue that customizing growth media composition to cell type will decrease the cost and waste associated with cultivated meat production.

Written by Morgan Ziegelski

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O’Neill, E. N., Ansel, J. C., Kwong, G. A., Plastino, M. E., Nelson, J., Baar, K., & Block, D. E. (2022). Spent media analysis suggests cultivated meat media will require species and cell type optimization. npj Science of Food, 6(1), 46. https://doi.org/10.1038/s41538-022-00157-z

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