Considerations for Development of Cost-Effective Cell Culture Media for Cultivated Meat Production

Overview

Who: Edward N. O'Neill, Zachary A. Cosenza, Keith Baar, David E. Block

Published: November 3, 2020

Where: Comprehensive Reviews in Food Science and Food Safety

Key Takeaway: Cell culture media for cultured meat can be made more cost-effective by researching alternatives for more expensive or unethical ingredients, specifically those used in differentiation.

Research Topics: media

Summary

Edward N. O’Neill et al. consider the technological progress of a cost-effective culture media for cultured meat, as well as remaining challenges in its development. Their review breaks down the components of traditional cell culture media, explores the purposes of the ingredients, and poses alternatives to the components that are more costly or unethical. O’Neill et al. suggest that media optimization ought to occur in the selection of components that induce differentiation and promote the specific growth of muscle cells. They argue that more insight into these mechanisms could elucidate mechanisms of self-sufficiency within the cells or alternative components. They also suggest taking cues from the optimization of culture media for large-scale microbial fermentation.

Written by Morgan Ziegelski

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O’Neill, E. N., Cosenza, Z. A., Baar, K., & Block, D. E. (2020). Considerations for the development of cost‐effective cell culture media for cultivated meat production. Comprehensive Reviews in Food Science and Food Safety, 20(1), 686-709. doi:10.1111/1541-4337.12678

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