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Overview
Who: Natalie R. Rubio, Kyle D. Fish, Barry A. Trimmer, and David L. Kaplan
Published: January 2, 2019
Where: ACS Biomaterials Science and Engineering
Key Takeaway: Insect cells can be grown successfully in culture and could be used for cell ag.
Research Topics:
cell
Summary
Natalie Rubio et al. evaluate the potential of invertebrate cells— specifically Drosophila melanogaster—for non-medical tissue engineering applications. The study finds that these insect cells are easier to grow and have many versatile features that would make them well-suited for culturing meat or bioactuation. For instance, compared with mouse myoblast cells in nutrient deficient conditions, these insect cells remain viable for significantly longer. Furthermore, Rubio et al. analyze edible scaffolds to support cell adhesion and assayed cellular protein and minerals to evaluate nutrition potential. They find that the protein, iron, and zinc contents of insect cells were higher than for mouse cells after correcting for cell size. This paper lays the groundwork for future research to assess the potential of insect muscle tissue engineering for cultured meat and bioactuation.
Written by Nick Johnson
Funding
Cite This Publication
Rubio, N. R., Fish, K. D., Trimmer, B. A., & Kaplan, D. L. (2019). In Vitro Insect Muscle for Tissue Engineering Applications. ACS Biomaterials Science & Engineering, 5(2), 1071–1082. https://doi.org/10.1021/acsbiomaterials.8b01261
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