- Cite This Publication
Who: Scott J. Allan, Paul De Bank, and Marianne J. Ellis
Published: June 12, 2019
Where: Frontiers in Sustainable Food Systems
Key Takeaway: While we can draw on lessons learned from other biotech industries, we still need more research to enhance the design of bioreactors to scale-up cultured meat production.
In this review, Scott J. Allan et al. examine the bioreactor specifications needed to scale up production within a full-scale cultured meat bioprocess. The review focuses on design considerations for the proliferation bioreactor, including configurations and cell growth components. Drawing on lessons learned from other relevant industries, Allan et al. quantify requirements for bioreactor sizing and passaging as it relates to cell density for several types of bioreactors. The paper describes the benefits and drawbacks of several large-scale cell culturing processes, and identifies areas of open research necessary to progress the nascent field.
Written by Morgan Ziegelski
Allan, S. J., De Bank, P. A., & Ellis, M. J. (2019). Bioprocess Design Considerations for Cultured Meat Production With a Focus on the Expansion Bioreactor. Frontiers in Sustainable Food Systems, 3, 44. https://doi.org/10.3389/fsufs.2019.00044
Isha Datar, Mirko Betti
Hanna L. Tuomisto, Scott J. Allan, Marianne J. Ellis
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